Make sure the printer is powered up. The DC power should be plugged in, it is the little round plug. The DC power is a laptop power supply. The big rectangle power supply. The fan should be spinning without a USB cable plugged into the printer. The controller should have a lit bright red LED. The on switch on the front of the printer should be pressed in and the light should shine bright.
Every Windows 10 PC we have used connected the printers automatically, but some of the users have reported that the PC didn't automatically detect the printer.
Steps to try
As is normal with Windows, restart if there is a problem. Before doing anything else, unplug the printer from the USB port and restart the PC. When the PC is up and running again plug the printer into a USB port. The PC should normally play a sound....